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ANALYSIS OF ANTIHZPERTENSIVETHERAPYIN PATIENTS WITH

                                                  ISCHEMIC STROKE
                                                       Filip Bošković
                                         Zemunska gimnazija, Zemun, filipbos26@gmail.com


         1. The purpose of the investigation
                                                                           No changes   Doses   Second AH drug   CCTP
         A stroke is the loss of brain function due to disturbance in
         the blood supply to the brain.Recent studies in Serbia show   TIA   12(19,1%)   21(33,4)   27(42,8)   3(4,7)
         that ischemic stroke (IMU) is the first cause of all deaths in
                                                                       IS   9(17,6%)   12(23,6)   24(47)   6(11,8)
         hospital, and is the second leading cause of death worldwide
         and an important cause of serious, long-term disability. The
         aim  of  the  research  is  the  analysis  of  therapeutic  program   ISS   33(17,7%)   57(30,5)   75(40,5)   21(11,2)
         from  the  aspect  of  increased  risk  for  the  emergence  and
                                                                      Total   54(18%)   90(30,0%)   126(42%)   30(10,0%)
         development  of  ischemic  stroke,  in  patients  with  ischemic
         stroke  (IS),  who  were  previously  been  on  antihypertensive
         (AH) therapy.                                            Tabel 2. Analysis of the therapeutic program in comparison
                                                                  to change modalities and degree of  IS severity
         2. Methods of the investigation
                                                                  In 18% of cases did not need to change the AH program,in
         The study included 300 patients (210 men and 90  women)   30%  of  cases,  adequate  control  has  been  achieved  by
         with AIS who had elevated blood pressure (21‚3 with 12,7   increasing the dose of already attributed drugs. Utilizationof
         kPa)before admission, who are known for hypertension and   second AH drugwas requiredin 42% and a complete change
         were  on  the  AH  therapy.  The  average  age  was  65.67   of the program in 10% of cases.It has been shown that 18%
         years.All  respondents  were  taken,  a  detailed  history  of  the   tookn  regular  therapy  and  check-ups  and  that  34%  of
         type AH drugs, therapy regularity and check-ups regularity.   patientsirregularly use therapy and are controlled irregularly.
         AH  therapy  includedcalcium  channel  blockers,  beta
         blockers,ACE   inhibitorsanddiuretics.Transient   ischemic   4. Conclusion
         attack (TIA)was measuredthe first 24 hours at 4 hours, and
         then 3 times per day. From the study were excluded patients   It  has  been  shownthat  diureticswere  the  most  commonly
         with certain types of illnesses due to the inability to obtain   used AH drugs. To nearly half of patients  were introduced
         valid data.                                              second AH drug due to differences in the type of illness and
                                                                  specificity of patients.Because of the fact that patients do not
         3. Results                                               realize seriousness of the event that they survived and that in
                                                                  a  short  period  after  a  stroke  give  up  the  recommended
                                                                  therapeutic  program  and  the  fact  that  the  profession
                  Ca blockers   B blockers   ACE inhibitors   Diuretics
                                                                  insufficiently  insisted  on  the  necessity  of  a  rigorous
                                                                  adherence  to  treatment  protocols,  neurologists  and  society
            TIA    24(57,1%)   21(33,3%)   33(52,3%)   30(47,6%)   today have a big problem.

             IS    27(52,9%)   15(29,4%)   27(52,9%)   33(64,7%)
                                                                  REFERENCES

            ISS    102(55%)   51(27,4%)   96(51.6%)   108(58%)
                                                                  [1] Albers GW, Easton JD, Sacco RL, Teal P.
                                                                  Antithrombotic and thrombolytic therapy for ischemic
         Tabel  1.  The  frequency  of  AH  therapy  compared  to  the   stroke. Chest. 1998;114:683S-698S.
         degree of severity of IS
                                                                  [2] Ţivković M, Šternić N, Kostić V. Ishemička bolest
         Diuretics are most commonly applied AH drugs (alone or in   mozga. Beograd: Zavod za udţbenike i nastavna sredstva,
         combination in 58% of cases), calcium channel blockers in   2000.
         55%, ACE inhibitors52%, beta blockers 29%.


         Acknowledgment: to colonel prof. D.N. Ranko Raičević, head of the Clinic of Neurology (MMA), for support and permission to
         take part in the regular activities of theClinic of Neurology
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